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Disorders of the urinary system -- including urinary incontinence -- may be
caused by illness, injury, or age-related physical changes, such as decreased
kidney function, loss of muscle strength in the urinary tract, and increased
numbers of urinary infections. However, urinary incontinence is not a certain
consequence of growing old and can occur at any age.
Many forms of urinary incontinence are short-term and can be managed with
simple therapy. Some temporary causes of urinary incontinence include:
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Infection and/or inflammation of the urinary tract, vagina or prostate
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Constipation (impacted stool)
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Psychological factors
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Mental delirium (confusion)
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Polyuria (increased production of urine)
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Limited mobility
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Side effects of medications
Urinary incontinence that is longer lasting or chronic may be caused by
conditions such as:
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Weakness of the muscles that support the bladder
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Weakness of the bladder itself
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Weakness of the sphincter muscles that surround the urethra
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Overactive bladder muscles
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Blocked urethra due to prostate enlargement
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Nerve disorders or injuries
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Birth defects
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Hormone imbalances in women
In addition, some unlikely diseases and medications have been linked with
urinary incontinence. Each case will vary, depending upon factors such as
the time course of the incontinence, as well as the age, gender and the
medical history of the affected person.

Childbirth
In women, incontinence is often related to pregnancy and childbirth, which
can flatten, stretch and weaken many of the pelvic floor muscles that provide
the necessary support to the bladder neck and urethra, and are therefore
important in urination. But, if a woman loses bladder control immediately
after childbirth, she should not despair. The pelvic floor muscles may just
need time to recover, and the incontinence may go away by itself.
If incontinence continues after 6 weeks, a physician should be contacted.
Without proper treatment, urinary incontinence can become a chronic problem.
Incontinence also may be caused by other aspects of pregnancy and childbirth,
such as a changed position of the bladder and urethra, episiotomy (a cut made
in the pelvic floor/vagina, which makes it easier for the baby to come out),
or damage to the bladder control nerves. Studies suggest that the more
vaginal births (births through the reproductive canal; non-ceasarean births)
a woman has had, the more likely she is to leak urine during physical activity.
Women who exercise the pelvic floor muscles usually have fewer bladder
problems than those who do not. Bladder control problems do not necessarily
occur immediately after childbirth. Some women do not begin to experience
incontinence problems until months or years after they have borne children.

Menopause
Between 45 and 55 years of age, most women's ovaries (egg-containing glands)
stop making estrogen: the female sex hormone that regulates monthly menstrual
periods and controls how the body matures and adapts during pregnancy and
breast-feeding. This reduction in estrogen causes menopause (the end of monthly menstrual periods). Lack of
estrogen can result in a urethra with a thin lining that does not close
properly. Lack of estrogen also makes the bladder muscles weaken. The
combination of a thin, injury-prone urinary tract and weak bladder muscles
can cause the urethra to open unexpectedly during physical activity, leading
to stress incontinence.
Some of the signs of menopause-related bladder changes include:
Fortunately, estrogen products are available for the treatment of
incontinence caused by menopause. Women who have such incontinence have the
option of choosing from a number of different forms of estrogen. However,
every woman who thinks about using estrogen therapy should discuss the pros
and cons with her physician. Estrogen products are available only by
prescription.

Pelvic Surgery
Like pregnancy and childbirth, pelvic surgery can weaken and damage the
pelvic floor muscles. As a result, the pelvic floor muscles may no longer
be able to provide the necessary support to the bladder neck and urethra,
and these structures may drop freely when downward pressure is applied.
This condition, which is known as hypermobility, causes incontinence during
physical activity, when the urethra cannot close tightly enough to resist
increased abdominal pressure on the bladder.
Urinary incontinence can result from common forms of pelvic surgery,
including abdominal resection for colorectal (intestinal) cancer, gynecologic
(female genital tract) surgery such as radical hysterectomy (complete removal
of the uterus) or hysterectomy for benign (noncancerous) disease, and failed
prolapse (restabilization) surgery for stress urinary incontinence.
Most patients with postoperative incontinence have either detrusor
instability (DI or unstable bladder: an involuntary, downward-pushing
contraction of the bladder) or urethral/bladder neck incontinence (abnormal
function) due to nerve damage. Successful management of DI incontinence
usually can be achieved by drug therapy and urinary catheterization (passage
of a tube through the urethra into the bladder to drain urine into a bag
outside the body); patients with bladder neck incontinence may require
additional surgical measures.

Diabetes mellitus
Diabetes mellitus is a disease that is characterized by producing large
amounts of urine. The bodily changes caused by diabetes can result in nerve
damage that affects the bladder. The bladder malfunction specifically
associated with diabetes mellitus is called diabetic cystopathy. Diabetic
cystopathy progresses with few noticeable symptoms, although patients may
lose bladder sensation. Over time, impaired bladder sensation may lead to
increased bladder volume and overdistension (overstretching), urinary
retention (bladder-emptying) problems, and
overflow incontinence. The few existing treatments for diabetic
cystopathy include catheterization, timed voids and control of hyperglycemia (too
much blood sugar).

Decreased Mobility
Decreased mobility is a cause of functional incontinence in older people who
have relatively normal bladder control but who have difficulty reaching the
toilet in time because of physical disorders (for example, arthritis and
other crippling conditions) or mental disabilities.

Diuretic Medications
Diuretics, or water pills, are prescribed by physicians to increase the
amount of urine that is released from a patient's body. Diuretics are
commonly used for the treatment of conditions such as hypertension (high
blood pressure) and edema (abnormal build-up of fluid in the body).
Unfortunately, rapid-acting diuretics can increase the urgency and frequency
of urination in some people, particularly those who are elderly and/or
bedridden. Urinary incontinence may result.
The unwanted side effects of diuretics can be remedied by lowering or
modifying the dosage of the medication: for example, by flexible scheduling
of rapid-acting diuretics.
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